Okay this can be fun now. With a few simple steps MSI gives us overclock options. You have seen the first one with the turnable knob.

Second will be what I am using: BIOS settings.

Third I can't show as I didn't got one but it is the OC-Panel.

MSI also has a option called Hotkey overclocking with your keyboard.

And you can overclock with software like MSI's Command Center:

Or with XTU:

But i prefer overclocking from the BIOS, and i will show here some settings; keep in mind I will am not establishing any records here! Just playing a bit with the settings. 

Let's hit that DEL button and play.

I want to get to 5000MHz like we did with the OC-Knob, but with higher Uncore and higher memory.

Manually I am setting the core and Uncore (ring ratio) to 50 and 49. Disabled the Game Boost OC Explore mode on expert. Disable EIST C-state etc.

Raising the CPU Core voltage to 1.475 and DRAM voltage to 1.5 resulting in:

Time to compare with the standard settings.